Beyond Sugar: What Cancer Cells Need to Grow Memorial Sloan Kettering Cancer Center Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Frontiers Glutathione responsive and exhausting metal nanomedicines for robust synergistic cancer therapy