Mini Review Acetaminophen Toxicity and 5 Oxoproline (Pyroglutamic Acid): A Tale of Two Cycles, One an ATP Depleting Futile Cycle The acetaminophen metabolite N acetyl p benzoquinone imine (NAPQI) inhibits glutathione synthetase in vitro; a clue to the mecha 5Oxoprolinase deficiency: report of the first human OPLAH mutation Glutathione
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5-oxoproline glutathione Recurrent High Anion Gap Metabolic Acidosis Secondary to 5-Oxoproline (Pyroglutamic Acid)