File:Pathology of G6PD deficiency.png Wikimedia Commons Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Glucose 6 phosphate dehydrogenase (G6PD): Response of the human erythrocyte and another cells to the decrease in their activity