Toxicity of Glutathione Binding Metals: A Review of Targets and Mechanisms Redox Directed Cancer Therapeutics: Molecular Mechanisms and Opportunities Georg T. Wondrak, 2009 Mycotoxins can deplete glutathione, a key antioxidant that helps maintain the blood brain barrier. Low glutathione may weaken the barrier, potentially worsening neuroinflammation in PANS PANDAS. Since mycotoxin exposure is frequently found in these Glutathione depletion induces oxidative injury and apoptosis via TRPM2 channel activation in renal collecting duct cells ScienceDirect
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mycotoxins deplete glutathione Mycotoxin-induced depletion of intracellular glutathione and altered cytokine production in the human alveolar epithelial cell line A549