The Hidden Risks of BPC157: What Patients Need to Know About Contamination and Safety Regenexx at New Regeneration Orthopedics Researchers found BPC 157 did something unusual in rodent models it reduced both dangerous blood clots AND excessive bleeding simultaneously, without directly touching the normal clotting cascade. Most drugs fight one problem 6 Blood Thinner Interactions: Medications and Supplements to Avoid GoodRx People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation.