Pigmented macular lip lesion Clinical Advisor Pigmented Lesions of the Oral Mucosa Springer Nature Link Oral Malignant Melanoma Oral Cancer Foundation Information and Resources about Oral Head and Neck Cancer An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic