Circulating Genotypes of Hepatitis C Virus in Italian Patients before and after the Application of Wider Access Criteria to HCV Treatment APASL consensus statements and management algorithms for hepatitis C virus infection Melanosis coli** Melanosis coli is a benign, reversible condition characterized by brown black pigmentation of the colonic mucosa, most often due to chronic use of anthraquinone laxatives. The discoloration is caused Nine year distribution pattern of hepatitis C virus (HCV) genotypes in Southern Italy PLOS One