Zepbound Outperforms CagriSema in Head to Head Phase III Obesity Trial Structural and mechanistic insights into dual activation of cagrilintide in amylin and calcitonin receptors Acta Pharmacologica Sinica For an adult with type 2 diabetes mellitus who requires substantial weight loss, what are the recommended use, dosing, regulatory approval status, and contraindications of tirzepatide compared with cagrilintide, and what alternative Tirzepatide: a new low for bodyweight and blood glucose The Lancet Diabetes & Endocrinology