The Roles of Glutathione and Oxidative Stress in Diabetes and COVID 19 Glutathione S transferases and oxidative stress in Saccharomyces cerevisiae Semantic Scholar Glutathione, often dubbed the master antioxidant plays a crucial role in detoxification, immune function, and protecting our cells from oxidative stress. Here are some signs that your levels might be low: Persistent Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme mimicking activities, and low molecular weight antioxidants Archives of Toxicology Springer Nature Link